METHODS FOR DRUG DELIVERY COMPRISING UNFOLDING AND FOLDING PROTEINS AND PEPTIDE NANOPARTICLES
摘要
The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.
申请公布号
EP2464224(A4)
申请公布日期
2014.03.05
申请号
EP20100808554
申请日期
2010.08.06
申请人
NANJING UNIVERSITY;NANJING EFFECT PHARM DRUG DEVELOPMENT CORPORATION