发明名称 A COMPOSITION FOR PROMOTING DIFFERENTIATION COMPRISING INDENONE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
摘要 The present invention relates to a composition for promoting differentiation of adult stem cell which includes indenone derivatives or pharmaceutically acceptable salts thereof, to a method for promoting differentiation from the adult stem cell into muscle cells, fat cells, or osteoclast which includes a step of culturing the adult stem cell under the presence of the composition, to a composition for reproducing muscles or fat tissues which includes the composition as an active ingredient, to a composition for preventing or treating muscle diseases, to a composition for preventing or treating fat deficiency diseases, to a composition for preventing or treating osteoclast deficiency diseases, and to a method for screening candidate substances which suppresses or induces differentiation of muscle cells, fat cells, or osteoclast of the adult stem cell which comprises the steps of: culturing the adult stem cell in a medium including the composition; processing the medium with candidate substances; and checking differentiation into the muscle cells, fat cells, or osteoclast before and after processing the candidate substances. [Reference numerals] (AA) Chemical formula 2 (micro M) + 2% horse serum (HS); (BB) Chemical formula 2 (micro M) + HS
申请公布号 KR20140025834(A) 申请公布日期 2014.03.05
申请号 KR20120092020 申请日期 2012.08.22
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 发明人 KIM, SEONG HWAN;SON, YOU HWA;HEO, JUNG NYOUNG
分类号 A61K31/04;A61P19/00;A61P21/00 主分类号 A61K31/04
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