发明名称 |
METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE |
摘要 |
Provided is a method of manufacturing a high quality phosphonocrotonic acid derivative. The present invention is a method of manufacturing a compound represented by the following Formula (3) by reacting a compound represented by the following Formula (1) with a compound represented by the following Formula (2), which comprises a treatment process using an acid or base. [in the formula, R 1 represents a C 1-6 linear or branched alkyl group that may be substituted by a C 6-10 aryl group, a C 2-6 linear or branched alkenyl group that may be substituted by a C 6-10 aryl group, a C 2-6 linear or branched alkynyl group that may be substituted by a C 6-10 aryl group, or a C 6-10 aryl group, R 2 represents a hydrogen atom, or a C 1-6 linear or branched alkyl group that may be substituted by a C 6-10 aryl group, R 3 represents a C 1-6 linear or branched alkyl group, a C 6-10 aryl group, or a halogen atom, and X represents a halogen atom, and multiple R 1 s may be the same or different]. |
申请公布号 |
EP2703407(A1) |
申请公布日期 |
2014.03.05 |
申请号 |
EP20120776934 |
申请日期 |
2012.04.26 |
申请人 |
KOWA COMPANY, LTD.;MANAC INC. |
发明人 |
INA, SHINJI;YAMAZAKI, TAKAHIRO;SAKATA, JUNICHI;EZAKI, KOJI;SAKAMOTO, KATSUHIRO |
分类号 |
C07F9/40;A61K9/10;A61K9/14;A61K9/16;A61K9/20;A61K9/48;A61K31/167;A61K31/202;A61K33/16;A61K35/74;A61K35/742;A61K35/744;A61K45/06;A61P35/00;C07C51/09;C07C51/353;C07C57/03;C07C67/343;C07C69/587 |
主分类号 |
C07F9/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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