| 摘要 |
The present invention relates to a method for preparing 1,3-substituted pyrazol compounds of formula (I)where X stands for a group CXXX, with X, Xand Xbeing hydrogen, fluorine or chlorine, independently of one another, Rbeing an C-Calkyl or cyclopropyl, and Rbeing hydrogen, CN or a group COR, where Rstands for C-Calkyl in particular, comprising the following steps: i) reacting a compound of formula II with a hydrazone of formula (III)wherein in formula (II) the variables X and Rhave the same meaning as indicated for formula (I), Y stands for oxygen, a group NRor a group [NRR]Z, Rstands for ORor a group NRR, and wherein in formula (III) the variable Rhas the same meaning as indicated for formula (I), Rand Rstand for hydrogen, C-Calkyl, alternatively substituted phenyl, independent of one another, wherein at least one of the radicals Ror Ris different from hydrogen and where Rand Rcan also stand for a 5- to 10-membered saturated carbocycle together with the carbon atom connected thereto; ii) treatment of the reaction product obtained thereby with an acid in the presence of water. |
