发明名称 |
PROCESS FOR THE PREPARATION OF MEMANTINE AND ITS HYDROCHLORIC ACID SALT FORM |
摘要 |
The present invention relates to the synthesis of 1-amino-3,5-dimethyladamantane ("memantine") and its hydrochloric acid salt form. In particular a new intermediate (N-chloroacetylamino-3,5-dimethyladamantane) for the synthesis of memantine as well as a new process for the preparation of memantine and its hydrochloric acid salt form using said intermediate is disclosed. |
申请公布号 |
EA019303(B1) |
申请公布日期 |
2014.02.28 |
申请号 |
EA20090000474 |
申请日期 |
2007.10.05 |
申请人 |
KRKA, D.D., NOVO MESTO |
发明人 |
TIHI JAROSLAV;MELEH MARIJA;VRECER FRANC;ZUPET ROK;PUCELJ JOZE;PELKO MITJA |
分类号 |
C07C233/06;A61K31/13;A61P25/16;A61P25/28;C07C209/62;C07C211/38 |
主分类号 |
C07C233/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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