FOUR BRANCHED DENDRIMER-PEG FOR CONJUGATION TO PROTEINS AND PEPTIDES
摘要
<p>A POLYMERIC DENDRIMER-LIKE STRUCTURE WITH FOUR BRANCHES OF MONOMETHOXY- POLYETHYLENE GLYCOL THAT CAN BE REPRESENTED AS: THE CARBOXYLIC GROUP OF THE PREVIOUS STRUCTURE CAN BE FUNCTIONALIZED FOR THE PRODUCTION OF CONJUGATES OF PHARMACEUTICAL INTEREST. THE BINDING OF THIS DENDRIMER-LIKE POLYETHYLENE GLYCOL TO THERAPEUTIC PROTEINS IMPROVES THEIR IN VITRO AND IN VIVO STABILITY.</p>
