4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one and an mtor inhibitor

摘要

602807 Disclosed is the use of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]- 1H-quinolin-2-one (dovitnib) or a tautomer thereof or a mixture thereof, or a pharmaceutically acceptable salt thereof, and at least one mTOR inhibitor in the manufacture of a medicament for the treatment and prevention of a proliferative disease or a mTOR dependent disease.