| 摘要 |
595382 Disclosed herein are methods of treating a proliferative disease in a subject, comprising administering to the subject a therapeutically effective amount of N-(5-tert-butyl-isoxazol-3-yl)-N’-{ 4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-y1]phenyl} urea, also known as AC220, having the structure of Formula A, and a nucleoside analog, a topoisomerase inhibitor or an anthracycline, or a combination thereof such as decitabine, azacitidine, clofarabine, cytarabine, cladribine, etoposide, idarubicin and daunorubicin. |
