发明名称 CYCLIC AMIDE DERIVATIVE
摘要 [Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogues and a prophylactic and/or therapeutic agent against diabetes, obesity, or the like. [Means of solving the problem] A compound of Formula (III): (where f is 0 to 2; g is 1 to 4; j is 0 to 3; k is 0 to 2; n is 0 to 2; p is 0 to 4; h is 0 to 3; q1 id 0 to 3; q2 is 0 or 1; r1 is 0 to 2 (with the proviso that q1+q2+r1 is 0 to 5); J1a is -CR11a-, N; J2 is -CR12aR12b-, -CR12c-; T is -CH2-, O, -S(O)i- (i is an integer of 0 to 2) or -NR7-; X is O, S, or -NR7-; ring A''' is a benzene ring, a pyridine ring; ring B' is a benzene ring, a pyridine ring, a pyrimidine ring; and R1 to R14 are specific groups), a salt of the compound, or a solvate of the salt or the compound.
申请公布号 US2014057871(A1) 申请公布日期 2014.02.27
申请号 US201214114017 申请日期 2012.04.11
申请人 OKANO AKIHIRO;OHKOUCHI MUNETAKA;MAKABE MUNEYOSHI;MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 OKANO AKIHIRO;OHKOUCHI MUNETAKA;MAKABE MUNEYOSHI
分类号 A61K31/69;A61K31/425;A61K31/4439;A61K31/54;A61K31/541;A61K31/549;A61K45/06;C07D275/03;C07D279/02;C07D285/10;C07D285/16;C07D417/12;C07D417/14;C07F5/04 主分类号 A61K31/69
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