发明名称 |
COMPOUNDS AS MODULATORS OF A MUTANT CFTR PROTEIN AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH CFTR PROTEIN MALFUNCTION |
摘要 |
The present invention relates to novel protein modulators capable of altering function of the mutant CFTR protein and their use for treating diseases associated with CFTR protein malfunction. The invention provides compositions, pharmaceutical preparations and methods of correcting the cellular alteration of a mutant CFTR protein wherein the CFTR mutation is a mutation ”F508-CFTR, or another mutation of class II. |
申请公布号 |
KR20140023866(A) |
申请公布日期 |
2014.02.27 |
申请号 |
KR20137009595 |
申请日期 |
2011.06.20 |
申请人 |
INSTYTUT BIOCHEMII I BIOFIZYKI PAN |
发明人 |
ODOLCZYK NORBERT;ZIELENKIEWICZ PIOTR;WIECZOREK GRZEGORZ;EDELMAN ALEKSANDER;TONDELIER DANIELLE;FRITSCH JANINE |
分类号 |
C07F9/30;A61K31/435;A61K31/663;A61P11/00;A61P13/00;C07D401/12;C07D473/30 |
主分类号 |
C07F9/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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