| 摘要 |
FIELD: biotechnologies.SUBSTANCE: pox virus of variolovaccine is proposed, which includes a defect F2L gene and a suicide gene. Pox virus has oncolytic activity. Besides, a reproduction method of such pox virus and its use for treatment of proliferative diseases or diseases with increased activity of osteoclasts is proposed.EFFECT: improving compound application efficiency.31 cl, 12 dwg, 3 tbl |
