DILUTION GUIDED CORRECTION (DGC) METHOD AND APPARATUS FOR ADJUSTING NONINVASIVELY MEASURED TOTAL HEMOGLOBIN MEASUREMENTS AND METHOD FOR EVALUATING HYDRATION STATE OF A SUBJECT USING THE SAME

摘要

Methods and devices are provided for real time adjustment of noninvasively measured capillary hemoglobin concentration measures for a prediction of invasively measured hemoglobin concentration in large vessels and evaluating and modifying the state of interstitial hydration of an individual by the mVLT method. Implication of mVLT was refined by adding new diagnostic criteria and new variables, also expanding its noninvasive applicability. That opens application in the automated clinical decision support systems, semi-closed and closed loop infusion systems for optimisation of hydration, blood circulation and tissues perfusion, also optimizing blood transfusions.