摘要 |
<p>The present invention relates to methods and compositions for delivering a vector comprising a nucleic acid to be expressed in the myocardium of a patient, as well as uses of vectors comprising a nucleic acid in the preparation of a medicament for the treatment of heart disease, wherein the medicament is for infusion into the myocardium through introduction into a coronary artery, and combinations comprising medicaments for the treatment of heart disease, wherein the medicament is for infusion into the myocardium through introduction into a coronary artery following induced occlusion, and a technique for optimizing delivery by occlusion of a coronary artery.</p> |