发明名称 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS
摘要 Antibody drug conjugates (ADC's) that bind to 158P1D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
申请公布号 WO2014032021(A1) 申请公布日期 2014.02.27
申请号 WO2013US56504 申请日期 2013.08.23
申请人 AGENSYS, INC.;SEATTLE GENETICS, INC.;MORRISON, ROBERT, KENDALL;AN, ZILI;MORRISON, KAREN JANE, MEYRICK;SNYDER, JOSH;JIA, XIAO-CHI 发明人 MORRISON, ROBERT, KENDALL;AN, ZILI;MORRISON, KAREN JANE, MEYRICK;SNYDER, JOSH;JIA, XIAO-CHI
分类号 A61K39/395;C07K19/00;C12N5/071;C12P21/08 主分类号 A61K39/395
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