发明名称 |
PHARMACEUTICAL COMPOSITION |
摘要 |
PROBLEM TO BE SOLVED: To provide a method of spray drying a drug (e.g., VX-950) or other therapeutic agent.SOLUTION: The invention provides a method of spray drying a drug (VX-950) or other therapeutic agent, the method comprising forming, in a suitable solvent or combination of solvents (at least one solvent is a non-volatile solvent), a mixture of the drug and solvent, and then spray drying the mixture to obtain an amorphous solid dispersion. |
申请公布号 |
JP2014037435(A) |
申请公布日期 |
2014.02.27 |
申请号 |
JP20130240174 |
申请日期 |
2013.11.20 |
申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
KEVIN JOHN BITTORF;KATSTRA JEFFREY P;FILIPE GASPAR |
分类号 |
A61K38/00;A61K9/14;A61K47/20;A61K47/22;A61K47/32;A61K47/34;A61K47/38;A61K47/40;A61P31/14;A61P43/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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