发明名称 SUBSTITUTED 3 - (THIAZOLE - 4 - CARBONYL) - OR 3 - (THIAZOLE - 2 - CARBONYL) AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS.
摘要 <p>The present invention relates to compounds of the formulae (Ia) and (Ib), wherein G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The invention furthermore relates to processes for the preparation of the compounds of the formulae la and lb, their use and pharmaceutical compositions comprising them.</p>
申请公布号 MX2014000596(A) 申请公布日期 2014.02.27
申请号 MX20140000596 申请日期 2012.07.25
申请人 SANOFI 发明人 SVEN RUF;JOSEF PERNERSTORFER;THORSTEN SADOWSKI;GEORG HORSTICK;HERMAN SCHREUDER;CHRISTIAN BUNING;KLAUS WIRTH
分类号 C07D277/54;A61K31/426;A61K31/427;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P13/00;C07D417/04 主分类号 C07D277/54
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