发明名称 NOVEL BENZIMIDAZOLE HEXAHYDROFURO[3,2-B]FURAN DERIVATIVES
摘要 The novel benzimidazole hexahydrofuro[3,2-B]furan derivatives of the present invention are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
申请公布号 WO2014031468(A1) 申请公布日期 2014.02.27
申请号 WO2013US55246 申请日期 2013.08.16
申请人 MERCK SHARP & DOHME CORP.;APGAR, JAMES, M.;ARASAPPAN, ASHOK;BIFTU, TESFAYE;CHEN, PING;FENG, DANQING;GUIDRY, ERIN;HICKS, JACQUELINE, D.;KEKEC, AHMET;LEAVITT, KENNETH, J.;LI, BING;SEBHAT, IYASSU;QIAN, XIAOXIA;WEI, LAN;WILKENING, ROBERT, R.;WU, ZHICAI 发明人 APGAR, JAMES, M.;ARASAPPAN, ASHOK;BIFTU, TESFAYE;CHEN, PING;FENG, DANQING;GUIDRY, ERIN;HICKS, JACQUELINE, D.;KEKEC, AHMET;LEAVITT, KENNETH, J.;LI, BING;SEBHAT, IYASSU;QIAN, XIAOXIA;WEI, LAN;WILKENING, ROBERT, R.;WU, ZHICAI
分类号 A01N43/50;A61K31/4184 主分类号 A01N43/50
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