发明名称 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER BY INDUCING DENDRITIC CELL-LIKE DIFFERENTIATION FROM MONOCYTES TO IMPROVE ANTICANCER IMMUNE ACTIVITY
摘要 According to the present invention, a composition for inducing or activating dendritic cell-like cells so as to treat or prevent cancer by immunotherapy is provided. Specifically, the following is provided: an agent for activating cancer immunity, which comprises, as an active ingredient, the following REIC protein: (a) a protein consisting of the amino acid sequence shown in SEQ ID NO: 2; or (b) a protein consisting of an amino acid sequence derived from the amino acid sequence shown in SEQ ID NO: 2 by substitution, deletion, or addition of one or more amino acid(s) and having the activity of inducing differentiation from monocytes into dendritic cell-like cells.
申请公布号 US2014056945(A1) 申请公布日期 2014.02.27
申请号 US201314071895 申请日期 2013.11.05
申请人 MOMOTARO-GENE INC. 发明人 KUMON HIROMI;NASU YASUTOMO;WATANABE MASAMI;KASHIWAKURA YUJI
分类号 A61K38/18 主分类号 A61K38/18
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