摘要 |
<p>A pharmaceutical composition comprises cinacalcet or its salt, solvate, derivative, hydrate, anhydrate, enantiomer, polymorph, prodrug or complex and at least one pharmaceutically acceptable polymer. A process for preparing a pharmaceutical composition comprising cinacalcet or its salt, solvate, derivative, hydrate, anhydrate, enantiomer, polymorph, prodrug or complex and at least one pharmaceutically acceptable polymer, comprises hot melt extrusion of the cinacalcet polymer blend to form extrudates and optionally mixing it with one or more pharmaceutically acceptable excipients.</p> |