发明名称 |
PROCESS FOR DELIVERING ENCAPSULATED NEUTRAL BIOIMAGING MOLECULES, COMPLEX, AND PROCESS THEREOF |
摘要 |
The present disclosure relates to delivering neutral bioimaging molecules encapsulated within icosahedral DNA capsules in vivo and in vitro. The present disclosure also discloses the entrapment of neutral bioimaging molecules like FITC dextran within the cavity of a DNA polyhedron without any molecular recognition or chemical conjugation between host (DNA icosahedron) and cargo (like FITC Dextran). This DNA polyhedron is structurally well defined and shows high encapsulation efficiency. The present disclosure also relates to complex formed due to the encapsulation of neutral bioimaging agents within icosahedral DNA capsules. |
申请公布号 |
US2014056818(A1) |
申请公布日期 |
2014.02.27 |
申请号 |
US201214114568 |
申请日期 |
2012.05.09 |
申请人 |
KRISHNAN YAMUNA;BHATIA DHIRAJ;NATIONAL CENTRE FOR BIOLOGICAL SCIENCES |
发明人 |
KRISHNAN YAMUNA;BHATIA DHIRAJ |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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