发明名称 MODIFIED HYBRIDIZATION PROBES
摘要 The invention relates to a method for detecting a nucleic acid of an organism in a composition, comprising the steps of, (i) amplifying the nucleic acid to be detected, (ii) during or after amplification, hybridizing to said nucleic acid to be detected a first probe that comprises an abasic site additionally optionally carrying a detectable label, (iii) wherein the position of the abasic site corresponds to a position in said nucleic acid to be detected, known to have a polymorphism in said organism, and wherein said nucleic acid is detected if hybridization occurs.
申请公布号 US2014057263(A1) 申请公布日期 2014.02.27
申请号 US201214006794 申请日期 2012.03.21
申请人 ENGEL HOLGER;AZZAWI ALEXANDER;DI PASQUALE FRANCESCA;QIAGEN GMBH 发明人 ENGEL HOLGER;AZZAWI ALEXANDER;DI PASQUALE FRANCESCA
分类号 C12Q1/68 主分类号 C12Q1/68
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