发明名称 PHARMACEUTICAL AGENT COMPRISING ANTI-BMP9 ANTIBODY AS ACTIVE INGREDIENT FOR TREATMENT OF ANEMIA SUCH AS RENAL ANEMIA AND CANCER ANEMIA
摘要 The present invention provides an anti-BMP9 (Bone morphogenetic protein-9) monoclonal antibody or an antibody fragment thereof binding to human BMP9, a hybridoma producing the antibody or the antibody fragment, a DNA encoding the antibody or the antibody fragment, a vector comprising the DNA, a transformant obtained by introduction of the vector, a method for preparing the antibody or the antibody fragment using the hybridoma or the transformant, and a therapeutic agent comprising the antibody or the antibody fragment as an active ingredient. Further, the present invention provides a pharmaceutical composition comprising the antibody or the antibody fragment as an active ingredient for the treatment of anemia such as renal anemia, cancer anemia or the like, and a method for treating anemia such as renal anemia, cancer anemia or the like using the same.
申请公布号 US2014056902(A1) 申请公布日期 2014.02.27
申请号 US201313933295 申请日期 2013.07.02
申请人 KYOWA HAKKO KIRIN CO., LTD 发明人 SHIMIZU KIYOSHI;YAMAZAKI YUJI;KUBOTA TSUGUO;KIMURA KANAME
分类号 A61K39/395;C07K16/18 主分类号 A61K39/395
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