发明名称 |
METHODS OF USE FOR MONOMETHYL FUMARATE AND PRODRUGS THEREOF |
摘要 |
<p>Methods of treating a disease in a patient comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound selected from: (i) monomethyl fumarate, (ii) a prodrug of monomethyl fumarate, and (iii) combinations thereof, wherein the disease is chosen from balo concentric sclerosis, bronchiolitis obliterans organizing pneumonia, central nervous system vasculitis, Charcott- Marie-Tooth Disease, childhood ataxia with central nervous system hypomyelination, diabetic retinopathy, graft versus host disease, monomelic amyotrophy, neurodegeneration with brain iron accumulation, neurosarcoidosis, pareneoplastic syndromes, subacute necrotizing myelopathy, Susac syndrome and transverse myelitis.</p> |
申请公布号 |
WO2014031901(A1) |
申请公布日期 |
2014.02.27 |
申请号 |
WO2013US56278 |
申请日期 |
2013.08.22 |
申请人 |
XENOPORT, INC.;CUNDY, KENNETH C.;LISSIN, DMITRI V;SHREENIWAS, REVATI |
发明人 |
CUNDY, KENNETH C.;LISSIN, DMITRI V;SHREENIWAS, REVATI;WUSTROW, DAVID J.;VIRSIK, PETER A.;GALLOP, MARK A. |
分类号 |
A61K31/225;A61K31/5375;A61K45/06;A61P17/06;A61P25/00;A61P29/00;A61P35/00;A61P37/00;A61P37/06;A61P43/00 |
主分类号 |
A61K31/225 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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