| 发明名称 |
ANTIBODIES THAT SPECIFICALLY BIND TO A BETA OLIGOMERS AND USE THEREOF |
| 摘要 |
The present inventors successfully produced monoclonal antibodies that are specific to only soluble A beta oligomers, but do not recognize soluble A beta monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease. |
| 申请公布号 |
EP2419447(A4) |
申请公布日期 |
2014.02.26 |
| 申请号 |
EP20100764291 |
申请日期 |
2010.04.16 |
| 申请人 |
IMMUNAS PHARMA, INC. |
发明人 |
YOKOSEKI, TATSUKI;OKAMOTO, YASUHIDE;UMEDA, MAKOTO;ITO, TOSHIYUKI;IMAI, YUKIHO;FUJII, SHINOBU;TAKAMATSU, NAOFUMI |
| 分类号 |
C07K16/18;A61K39/395;A61P25/28;C12N15/09;G01N33/53;G01N33/68 |
主分类号 |
C07K16/18 |
| 代理机构 |
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