发明名称 |
PROCESS FOR PREPARING VACCINE COMPOSITION |
摘要 |
A method of preparing a composition comprising one or more antigens adsorbed to an amino acid wherein said method comprises: (i) mixing a solution of one or more antigens with a solution of the amino acid in an aqueous acid whilst neutralising the mixture of solutions, thereby forming an adsorbate comprising the one or more antigens and the amino acid; (ii) separating the adsorbate into a desired buffer by cross-flow filtration thereby forming said composition; and (iii) recovering said composition; wherein steps (i) to (iii) are performed in a sterile environment and within a closed system. |
申请公布号 |
EP2699255(A1) |
申请公布日期 |
2014.02.26 |
申请号 |
EP20120719034 |
申请日期 |
2012.04.20 |
申请人 |
ALLERGY THERAPEUTICS (UK) LIMITED |
发明人 |
SKINNER, MURRAY;HEWINGS, SIMON;PACKER, DUNCAN;POLAND, RICHARD |
分类号 |
A61K9/14;A61K39/00;A61K39/36 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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