发明名称 DRUG DELIVERY PARTICLES AND METHOD FOR PRODUCING SAME
摘要 An object of the present invention is to develop and provide a method for conveniently introducing a nucleic acid, a peptide, and/or a low-molecular-weight compound into an empty capsid with viral early infection activities kept. The present invention provides a method for producing a drug delivery particle, comprising the steps of: mixing an empty capsid or an empty particle with a drug including a nucleic acid, a peptide, and/or a low-molecular-weight compound in a solution comprising 0.1 to 20% of a surfactant; and keeping the obtained mixed solution at -5 to 50°C to introduce the drug into the empty capsid or the empty particle.
申请公布号 EP2700399(A1) 申请公布日期 2014.02.26
申请号 EP20120773753 申请日期 2012.04.16
申请人 NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY 发明人 OKADA TAKASHI;TAKEDA SHIN'ICHI;KINOH HIROMI
分类号 A61K9/50;A61K38/00;C12N5/10;C12N7/02;C12N15/09;C12P21/02 主分类号 A61K9/50
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