发明名称 |
Anti-(influenza a virus subtype H5 hemagglutinin) monoclonal antibody |
摘要 |
A method of immunoassay of H5 subtype influenza A virus by which the virus can be accurately assayed even in cases where a certain level of mutation has occurred in the H5 subtype influenza A virus, and a kit therefor, and a novel anti-H5 subtype influenza A virus monoclonal antibody which can be used for the immunoassay are disclosed. The antibody or an antigen-binding fragment thereof of the present invention undergoes antigen-antibody reaction with hemagglutinin of H5 subtype influenza A virus, and the corresponding epitope of the antibody or an antigen-binding fragment thereof is located in a region other than the receptor subdomain (excluding C-terminal region thereof consisting of 11 amino acids), which antibody or an antigen-binding fragment thereof does not have neutralizing activity against the influenza A virus. |
申请公布号 |
US8658354(B2) |
申请公布日期 |
2014.02.25 |
申请号 |
US20090934908 |
申请日期 |
2009.03.26 |
申请人 |
KIDA HIROSHI;SAKODA YOSHIHIRO;MIYAGAWA EIJI;FUJII NOBUYUKI;UCHIDA YOSHIAKI;SHIRAKAWA TAKASHI;KOGAKI HIROYUKI;NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;FUJIREBIO INC. |
发明人 |
KIDA HIROSHI;SAKODA YOSHIHIRO;MIYAGAWA EIJI;FUJII NOBUYUKI;UCHIDA YOSHIAKI;SHIRAKAWA TAKASHI;KOGAKI HIROYUKI |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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