发明名称 |
HLA ALLELES ASSOCIATED WITH ADVERSE DRUG REACTIONS AND METHODS FOR DETECTING SUCH |
摘要 |
This invention relates to a method of determining the presence of certain HLA alleles, such as HLA-B*1502 or HLA-B*5801, and a kit for carrying out this method. Also disclosed is a method for assessing whether a patient is at risk for developing adverse drug reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, or hypersensitivity syndrome) based on the presence or absence of a genetic marker (e.g., HLA-B*1502, HLA-B*5801, or HLA-B*4601). |
申请公布号 |
CA2651954(C) |
申请公布日期 |
2014.02.25 |
申请号 |
CA20072651954 |
申请日期 |
2007.05.11 |
申请人 |
ACADEMIA SINICA;PHARMIGENE INC. |
发明人 |
CHEN, YUAN-TSONG;HUNG, SHUEN-LU;SHEN, CHIH-LUNG;CHANG, CHI-FENG;LIN, HSIN-YU;CHEN, WEI-HSUAN |
分类号 |
C12Q1/68;C12P19/34;C12Q1/02;G01N33/15;G01N33/543 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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