发明名称 Verfahren zur Herstellung von Pyrrolidinverbindungen
摘要 <p>Hypoglycaemic 1-carbamoyl and -thiocarbamoyl-2-imino pyrrolidines. M3A. Compounds of formula (I):- (where R1= Ph opt. substd. by alkyl, alkoxy or halogen; R2= Ph opt. substd. by alkyl, alkoxy or halogen, cycloalkyl, cycloalkenyl; R3=R6=H or lower alkyl; R7= H, alkyl, carbalkoxyalkyl, dialkylaminoalkyl, alkoxyphenyl or alkoxyalkyl; X= O or S). are new compounds having hypoglycaemic activity. Preferred compounds include 1-(N-methoxymethyl)-thiocarbamoyl-2-imino-3,3-diphenyl-5-methyl-p- yrrolidine (X).</p>
申请公布号 CH500186(A) 申请公布日期 1970.12.15
申请号 CH19700016737 申请日期 1968.08.07
申请人 F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT 发明人 DR. BRETSCHNEIDER,HERMANN,PROF.;KLOETZER,WILHELM,DR.;FRANZMAIR,RUDOLF,DR.
分类号 C07D207/22;C07D207/26;(IPC1-7):C07D27/04 主分类号 C07D207/22
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