发明名称 |
Verfahren zur Herstellung von Pyrrolidinverbindungen |
摘要 |
<p>Hypoglycaemic 1-carbamoyl and -thiocarbamoyl-2-imino pyrrolidines. M3A. Compounds of formula (I):- (where R1= Ph opt. substd. by alkyl, alkoxy or halogen; R2= Ph opt. substd. by alkyl, alkoxy or halogen, cycloalkyl, cycloalkenyl; R3=R6=H or lower alkyl; R7= H, alkyl, carbalkoxyalkyl, dialkylaminoalkyl, alkoxyphenyl or alkoxyalkyl; X= O or S). are new compounds having hypoglycaemic activity. Preferred compounds include 1-(N-methoxymethyl)-thiocarbamoyl-2-imino-3,3-diphenyl-5-methyl-p- yrrolidine (X).</p> |
申请公布号 |
CH500186(A) |
申请公布日期 |
1970.12.15 |
申请号 |
CH19700016737 |
申请日期 |
1968.08.07 |
申请人 |
F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT |
发明人 |
DR. BRETSCHNEIDER,HERMANN,PROF.;KLOETZER,WILHELM,DR.;FRANZMAIR,RUDOLF,DR. |
分类号 |
C07D207/22;C07D207/26;(IPC1-7):C07D27/04 |
主分类号 |
C07D207/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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