发明名称 |
NOVEL TRIAZOLOPYRAZINE DERIVATIVES AND USE THEREOF |
摘要 |
The present invention relates to novel triazolopyrazine derivatives or a pharmaceutically acceptable salt, and a pharmaceutical composition for inhibiting c-Met tyrosine kinase activity and a pharmaceutical composition for preventing or treating hyperproliferative disorders, containing the same as active ingredients. The present invention effectively inhibits c-Met tyrosine kinase activity, thereby being able to be useful as a drug for various hyperproliferative disorders such as cancers, psoriasis, rheumatoid arthritis, diabetic retinitis, etc. related to excessive cell proliferation and growth by abnormal kinase activation. |
申请公布号 |
KR20140022229(A) |
申请公布日期 |
2014.02.24 |
申请号 |
KR20120088577 |
申请日期 |
2012.08.13 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK INC. |
发明人 |
JUNG, HEE JUNG;HA, JAE DU;CHO, SUNG YUN;KIM, HYOUNG RAE;LEE KWANG HO;LEE, CHONG OCK;CHOI, SANG UN;PARK, CHI HOON |
分类号 |
C07D487/04;A61K31/4985;A61P35/00;C07D403/14 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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