| 摘要 |
The present invention relates to a method for predicting chloasma formation and a diagnostic kit for chloasma formation and, more specifically, to a method for predicting chloasma formation and a diagnostic kit for chloasma formation, capable of diagnosing the possibility of chloasma formation on the skin by confirming the expression levels of genes which are differently expressed between the chloasma tissue and the normal skin tissue, wherein the diagnostic kit comprises: at least one polynucleotide sequence or its complementary polynucleotide as a probe hybridizing with polynucleotide of the gene sequence; a primer pair of the polynucleotide of the gene sequence; or at least one monoclonal antibody having, as a variable region, an amino acid sequence coded by the gene. According to the present invention, 23 high-expression genes and five low-expression genes, which are specific to a chloasma lesion, are used as a chloasma marker gene, thereby precisely and promptly diagnosing the possibility of chloasma formation on the skin. [Reference numerals] (AA) Relative mRNA expression level of a chloasma region as compared with a normal region; (BBC) Normal region |
