发明名称 METHODS AND COMPOSITIONS FOR MODULATING LYMPHANGIOGENESIS, E.G., TO TREAT TRANSPLANT REJECTION, IN A SUBJECT
摘要 Methods of modulating the occurrence of lymphangiogenesis in a subject are provided. In some instances, the method is a method of treating transplant rejection in the subject. Aspects of the methods include administering to the subject an effective amount of: a first antagonist for a tyrosine kinase receptor and a second antagonist for an integrin receptor. In some embodiments, the methods include enhancing survival of transplanted tissue in a subject. Aspects of the invention further include compositions, e.g., pharmaceutical compositions and kits that find use in methods of the invention.
申请公布号 US2014050742(A1) 申请公布日期 2014.02.20
申请号 US201313966760 申请日期 2013.08.14
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 CHEN LU
分类号 A61K39/395 主分类号 A61K39/395
代理机构 代理人
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