USE OF CHRYSALIS OIL FOR IMPROVING BIOAVAILABILITY OF SMALL MOLECULE DRUG

摘要

The present invention relates to a use of chrysalis oil for improving bioavailability of a small molecule drug, and belongs to the field of biological medicine. The present invention uses mainly a silkworm as a material, finds the chrysalis oil, i.e. a chrysalis component which is effective to improve the bioavailability of the small molecule drug (puerarin), and validates and calculates the results. The results show that the bioavailability is improved by 4.7 times relative to a control, and up to 6-9 times relative to the control with regard to the 30 min timepoint. The chrysalis oil is safe and stable, has no toxic side effect and has an extremely wide application prospect.