发明名称 |
INHIBITORS OF THE ACTIVITY OF COMPLEX III OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AND USE THEREOF FOR TREATING DISEASES |
摘要 |
The present invention relates to compounds which are inhibitors of the activity of Complex III of the mitochondrial electron transport chain and pharmaceutical compositions comprising said compounds alone or in combination with other active agents. The present invention further relates to use of the compounds of the invention as medicaments or as agrochemicals where their properties as inhibitors of the mitochondrial respiration is of benefit. More particularly the present invention relates to the use of the compounds of the invention in a method of treating and/or preventing cancers presenting tumor-initiating cells. (Formula I) (I) |
申请公布号 |
US2014051678(A1) |
申请公布日期 |
2014.02.20 |
申请号 |
US201113989319 |
申请日期 |
2011.11.24 |
申请人 |
CLEMENT-SCHATLO VIRGINIE;FESSARD THOMAS;CRIBIU RICCARDO;STEMERGIE BIOTECHNOLOGY SA |
发明人 |
CLEMENT-SCHATLO VIRGINIE;FESSARD THOMAS;CRIBIU RICCARDO |
分类号 |
C07D491/107;A61K31/167;A61K31/365;A61K31/397;C07C235/62;C07D267/00;C07D321/00 |
主分类号 |
C07D491/107 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|