发明名称 |
NOVEL KAPPA OPIOID LIGANDS |
摘要 |
The invention provides novel ligands of Kappa (&kgr;) opioid receptors, such as can be used to modulate a Kappa opioid receptor. Methods of synthesis and methods of use are also provided. Compounds of the invention can be used therapeutically in the treatment of dissociative disorders or pain, or to provide neuroprotection, or to induce diuresis, or to modulate the immune system, or for treatment of one or more of an affective disorders comprising depression or stress/anxiety; an addictive disorder; alcoholism, epilepsy; a cognition deficiency; schizophrenia; Alzheimer's disease; or pain. |
申请公布号 |
WO2014028829(A1) |
申请公布日期 |
2014.02.20 |
申请号 |
WO2013US55313 |
申请日期 |
2013.08.16 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ROBERTS, EDWARD;GUERRERO, MIGUEL A.;URBANO, MARIANGELA;ROSEN, HUGH |
分类号 |
A61K31/435;A61K31/4545;A61P25/04;A61P25/28;A61P37/02 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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