发明名称 |
RECOMBINANT INFLUENZA VIRUSES AND CONSTRUCTS AND USES THEREOF |
摘要 |
Disclosed are compositions and methods comprising one or more recombinant influenza viruses. Recombinant influenza viruses with mutated polymerases and/or rearranged genomes are disclosed. Constructs comprising different influenza nucleic acid sequences are also provided. Methods of inducing protecting immunity with the recombinant influenza viruses are disclosed. Also disclosed are methods of plasmid-free production of influenza virus comprising amplicons comprising one or more of influenza genes. |
申请公布号 |
WO2013177595(A3) |
申请公布日期 |
2014.02.20 |
申请号 |
WO2013US42932 |
申请日期 |
2013.05.28 |
申请人 |
UNIVERSITY OF MARYLAND |
发明人 |
PEREZ, DANIEL, R.;CHEN, HONGJUN;CAI, YIBIN;PENA, LINDOMAR, JOSE;ANGEL, MATTHEW |
分类号 |
A61K39/145;C12N7/00;C12N7/02;C12N7/04 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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