The present invention relates to prodrugs or a pharmaceutically acceptable salt thereof comprising a covalent treprostinil carrier conjugate as well as pharmaceutical composition comprising said compounds. The compounds may be used as medicaments, especially for diseases or disorders which can be treated by treprostinil, such as pulmonary arterial hypertension (PAH).
申请公布号
AU2012296954(A1)
申请公布日期
2014.02.20
申请号
AU20120296954
申请日期
2012.08.10
申请人
ASCENDIS PHARMA A/S
发明人
HERSEL, ULRICH;RAU, HARALD;LESSMANN, TORBEN;BISEK, NICOLA;MAITRO, GUILLAUME;SPROGOE, KENNETT;WEGGE, THOMAS;KEIL, OLIVER;ZETTLER, JOACHIM