发明名称 |
AMINOPYRIMIDINE KINASE INHIBITORS |
摘要 |
<p>Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CKlϒ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFPβpathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CKlϒ), casein kinase 2 (CK2), Pim- 1, Pim-2, Pim-3, the TGFPβpathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway.</p> |
申请公布号 |
WO2012145617(A9) |
申请公布日期 |
2014.02.20 |
申请号 |
WO2012US34436 |
申请日期 |
2012.04.20 |
申请人 |
JASCO PHARMACEUTICALS, LLC;BALDINO, CARMEN, M.;CASERTA, JUSTIN, L.;LEE, CHEE-SENG;DUMAS, STEPHANE, A.;FLANDERS, YVONNE, L. |
发明人 |
BALDINO, CARMEN, M.;CASERTA, JUSTIN, L.;LEE, CHEE-SENG;DUMAS, STEPHANE, A.;FLANDERS, YVONNE, L. |
分类号 |
C07D417/02;A61K31/495;A61K31/505;A61K31/506;C07D403/14;C07D417/06;C07D417/14 |
主分类号 |
C07D417/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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