发明名称 |
Artificial valved conduits for cardiac reconstructive procedures and methods for their production |
摘要 |
Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient. |
申请公布号 |
AU2012290221(A1) |
申请公布日期 |
2014.02.20 |
申请号 |
AU20120290221 |
申请日期 |
2012.07.30 |
申请人 |
CARNEGIE MELLON UNIVERSITY |
发明人 |
YOSHIDA, MASAHIRO;BERNSTEIN, C. DOUGLAS;DUR, ONUR;PEKKAN, KEREM |
分类号 |
A61F2/24 |
主分类号 |
A61F2/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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