发明名称 FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS
摘要 <p>Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease.</p>
申请公布号 EP2697227(A1) 申请公布日期 2014.02.19
申请号 EP20120715295 申请日期 2012.04.12
申请人 NEWLINK GENETICS CORPORATION 发明人 MAUTINO, MARIO;KUMAR, SANJEEV;WALDO, JESSE;JAIPURI, FIROZ;KESHARWANI, TANAY;ZHANG, XIAOXIA
分类号 C07D487/04;A61K31/4188;A61P37/02 主分类号 C07D487/04
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