| 摘要 |
The present invention relates to a use of haloid acid salt and sulfonate of a compound of formula I and a salt of the compound of formula I in preparation of medicament for preventing or treating diseases caused by thrombosis or embolism. The present invention provides acid addition salts, especially haloid acid and sulfonic acid addition salts of a compound of formula I having high inhibition effect on platelet aggregation, and preparation method of the same, a medicament comprising the same, and a use and/or method for preventing or treating diseases caused by thrombosis or embolism. The present invention discloses the hydrohalic acid and sulfonic acid addition salts of the compound of general formula I, their preparation process, and their use in manufacture of a medicament for treating or preventing thrombus or embolism. The salts of the present invention are more stable that the free compound pre se, possess good oral absorption and excellent inhibitory effect on platelet aggregation and stability with high potential to be an anti-thrombotic agent. |
