发明名称 |
ANTIBODY AND ANTIGEN RECOGNIZING TUMOR-INITIATING CELLS AND USE THEREOF |
摘要 |
Disclosed is a method for searching, identifying, or validating a marker CACNA2D1 of tumor-initiating cells. The method comprises a step of immunizing an animal using HEP-12 cells originating from a recurrent tumor and rich in originating cells. Also disclosed is a monoclonal antibody specially recognizing CACNA2D 1 or antigen-binding fragments thereof, and the use thereof for treating or preventing tumors or diseases or conditions related to CACNA2D1. |
申请公布号 |
KR20140020922(A) |
申请公布日期 |
2014.02.19 |
申请号 |
KR20137024482 |
申请日期 |
2012.02.22 |
申请人 |
BEIJING INSTITUTE FOR CANCER RESEARCH |
发明人 |
ZHANG ZHIQIAN;ZHAO WEI;WANG LIMIN;HAN HAIBO;XING BAOCAI |
分类号 |
C07K16/30;A61K39/395;A61P35/00;G01N33/577 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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