发明名称 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
摘要 The present invention relates to 2′-Cyano Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2′-Cyano Substituted Nucleoside Derivative, and methods of using the 2′-Cyano Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
申请公布号 EP2696679(A2) 申请公布日期 2014.02.19
申请号 EP20120770821 申请日期 2012.04.11
申请人 MERCK SHARP & DOHME CORP. 发明人 GIRIJAVALLABHAN, VINAY;NJOROGE, F. GEORGE;BOGEN, STEPHANE;KEREKES, ANGELA;BENNETT, FRANK;HUANG, YING;NAIR, LATHA;PISSARNITZKI, DIMITRI;VERMA, VISHAL;DANG, QUN;DAVIES, IAN;OLSEN, DAVID, B.;STAMFORD, ANDREW;VACCA, JOSEPH, P.
分类号 C07H19/10;A61K31/7056;A61K31/7068;A61P31/12;C07H19/20 主分类号 C07H19/10
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