发明名称 Intermediates useful in the preparation of maleimide functionalized polymers
摘要 Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the intermediates, are also provided. Also provided are polymeric reagents, methods of using polymeric reagents, compounds and conjugates.
申请公布号 US8653286(B2) 申请公布日期 2014.02.18
申请号 US201213568518 申请日期 2012.08.07
申请人 MCMANUS SAMUEL P.;KOZLOWSKI ANTONI;HUTCHISON TRACY L.;BRAY BRIAN;SHEN XIAOMING;NEKTAR THERAPEUTICS 发明人 MCMANUS SAMUEL P.;KOZLOWSKI ANTONI;HUTCHISON TRACY L.;BRAY BRIAN;SHEN XIAOMING
分类号 C07D207/448;A61K47/48;C08G65/333;C08G69/08 主分类号 C07D207/448
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