PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS.
摘要
A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.
申请公布号
MX2013014892(A)
申请公布日期
2014.02.17
申请号
MX20130014892
申请日期
2012.06.25
申请人
MERCK SHARP & DOHME LIMITED
发明人
KUETHE, JEFFREY T.;JANEY, JACOB M.;ZACUTO, MICHAEL J.;DUNN, ROBERT F.;MOMENT, AARON J.;LIEBERMAN, DAVID;SHEEN, FAYE;BREMEYER, NADINE;SCOTT, JEREMY