| 发明名称 |
AUTISM MODEL MOUSE BY SHANK2 GENE DELETION AND THE USE THEREOF |
| 摘要 |
The present invention relates to an autism model transformant which SHANK2 gene is deleted and the function of a NMDA receptor is reduced. According to the present invention, a transgenic mouse showing clinical features of autism due to a deletion of SHANK2 gene can be obtained and the invention can be used for selecting candidate substances of autism medications. |
| 申请公布号 |
KR20140019208(A) |
申请公布日期 |
2014.02.14 |
| 申请号 |
KR20120156048 |
申请日期 |
2012.12.28 |
| 申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY;SNU R&DB FOUNDATION;KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
KIM, EUN JOON;KANG, BONG KIUN;LEE, MIN GOO |
| 分类号 |
A01K67/027;C12N5/10;C12N15/63;G01N33/15 |
主分类号 |
A01K67/027 |
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