发明名称 |
1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS |
摘要 |
This invention relates to compounds of the formula wherein and R1 to R3 are as described herein, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as pharmaceuticals for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders. |
申请公布号 |
KR20140019353(A) |
申请公布日期 |
2014.02.14 |
申请号 |
KR20137024767 |
申请日期 |
2012.02.13 |
申请人 |
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A. |
发明人 |
HILPERT HANS;NARQUIZIAN ROBERT |
分类号 |
C07D267/10;A61K31/553;A61P3/10;A61P9/00;A61P25/28 |
主分类号 |
C07D267/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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