发明名称 USE OF (S)-ESMOLOL FOR CONTROLLING VENOUS IRRITATION ASSOCIATED WITH THE TREATMENT OF A CARDIAC DISORDER
摘要 A pharmaceutical composition comprising (S)-methyl-3-[4-(2-hydroxy-3-isopropylamino)propoxy]phenylpropionate in a concentration between about 75 mM and about 150 mM, which is substantially free of the R-isomer or pharmaceutically acceptable salt thereof, is provided. A method of treating a cardiac disorder is also provided and includes administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising (S)-methyl-3-[4-(2-hydroxy-3-isopropylamino)propoxy]phenylpropionate hydrochloride, wherein the (S)-methyl-3-[4-(2-hydroxy-3-isopropylamino)propoxy]phenylpropionate hydrochloride is present at a concentration between about 75 mM and about 150 mM and wherein the pharmaceutical composition is substantially free of (R)-methyl-3-[4-(2-hydroxy-3-isopropylamino)propoxy]phenylpropionate or pharmaceutically acceptable salt thereof.
申请公布号 KR20140019334(A) 申请公布日期 2014.02.14
申请号 KR20137022490 申请日期 2012.01.26
申请人 BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE SA 发明人 GASS JEROME H.;MCKEE JEFF;RABINOW BARRETT
分类号 A61K31/24;A61P9/06 主分类号 A61K31/24
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