发明名称 ANILIDE DERIVATIVE AS IN VIVO CONTRAST MEDIUM AND FLUORINATION METHOD OF BENZOTHIAZOLE FLUORINATE
摘要 PROBLEM TO BE SOLVED: To provide a method of manufacturing a compound of benzothiazole fluorinate derivative of the formula (I).SOLUTION: A method of manufacturing a compound of the formula (I) includes reacting a compound of the formula (II) with a fluoride (preferably [F]fluoride). In the formulas (I), (II), Ris selected from Calkyl, Calkenyl and Calkynyl, Ris selected from a hydrogen atom, Calkyl, Chaloalkyl, Caryl, Carylalkyl and -(CHCHO)-CH, where q is an integer of 1 to 10, Ris as defined for the compound of the formula (I), and Ris a leaving group.
申请公布号 JP2014028837(A) 申请公布日期 2014.02.13
申请号 JP20130196384 申请日期 2013.09.24
申请人 GE HEALTHCARE LTD;GE HEALTHCARE AS 发明人 ANTHONY EAMON STOREY;CLARE LOUISE JONES;BOUVET DENIS RAYMOND CHRISTOPHE;LASBISTES NICOLAS;FAIRWAY STEVEN MICHAEL;LORENZO WILLIAMS;GIBSON ALEXANDER MARK;ROBERT JAMES NAIRNE;FARHAD KARIMI;LANGSTROM BENGT
分类号 C07D277/66;A61K51/00 主分类号 C07D277/66
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