发明名称 |
A NOVEL TM4SF5 SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF |
摘要 |
The present invention relates to a novel monoclonal antibody which is specifically bound to a transmembrane 4 L six family member 5 (TM4SF5) protein. More particularly, the present invention relates to a monoclonal antibody which is specifically bound to a human TM4SF5 protein, to polynucleotides coding for the monoclonal antibody, to an expression vector comprising the polynucleotides, to a transformant with the vector introduced thereto, to a method for preparing the monoclonal antibody, to a pharmaceutical composition for preventing or treating cancer comprising the monoclonal antibody, to a method for treating cancer using the monoclonal antibody, to a method for providing information for diagnosing cancer using the monoclonal antibody, to a composition for diagnosing cancer comprising the monoclonal antibody, and to a cancer diagnosis kit comprising the composition for diagnosing cancer. |
申请公布号 |
KR20140018819(A) |
申请公布日期 |
2014.02.13 |
申请号 |
KR20130092805 |
申请日期 |
2013.08.05 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;SNU R&DB FOUNDATION |
发明人 |
KIM, SE MI;KIM, SANG JICK;MIN, HYE JIN;SONG, JIN MYEONG;LEE, JUNG WEON;KIM, HYE JIN |
分类号 |
C07K16/28;A61K39/395;A61P35/00;G01N33/574 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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